United States18 November 2024

ACR Convergence 2024 - Octapharma Innovation Theater

Beyond the Basics: What Makes Immunoglobulin Therapy Effective in Dermatomyositis?

Join our Innovation Theater in Washington D.C. and visit us at the Octapharma booth (#2341) in the exhibition area!

Introduction

While the use of Intravenous Immunoglobulin (IVIg) in autoimmune disorders like dermatomyositis is known for its effectiveness and widely used in clinical practice, the precise molecular mechanisms underlying its therapeutic effects have not been fully elucidated.

During this session Prof. Lisa Christopher-Stine will provide a comprehensive overview of immunoglobulin therapy, exploring the complex, multi-faceted mechanism through which IVIg works in managing conditions such as dermatomyositis, as well as in mitigating infection risks for dermatomyositis patients undergoing other immunosuppressive therapy. Through this session, attendees will gain a deeper understanding of how to effectively utilize IVIg to enhance patient outcomes. 

Prof. Rohit Aggarwal will further illustrate the therapeutic potential of IVIg by sharing insights from phase 3 clinical data in dermatomyositis. After discussing how IVIg has influenced treatment approaches for dermatomyositis, his presentation will focus on the impact of baseline variables, such as autoantibody status, on treatment response.

The session will conclude with an interactive discussion, inviting the audience to engage with the faculty.

Program

Beyond the Basics: What Makes Immunoglobulin Therapy Effective in Dermatomyositis?

Monday, November 18, 2024
12:30 - 01:15 pm
Theater A

Program

Speaker

Welcome and Introduction

Rohit Aggarwal

Unraveling the Mechanisms of Action of Immunoglobulins in Dermatomyositis

Lisa Christopher-Stine

Further Learnings from Phase 3 Clinical Data

Rohit Aggarwal

Q&A and Closing Remarks

Lisa Christopher-Stine, Rohit Aggarwal

For healthcare professionals only. This program is developed and offered by Octapharma. This is not an official program of the American College of Rheumatology

Speakers

Lisa Christopher-Stine, MD, MPH, is a Professor of Medicine and Neurology and the Director of the Johns Hopkins Myositis Center.

As a clinician scientist, Prof. Christopher-Stine utilizes the Myositis Database developed by her, as Principal Investigator, and her colleagues, currently numbering over 3000 patients worldwide. She has a strong interest in patient-reported outcomes and has been the co-chair of an international effort through the OMERACT organization to develop a novel patient reported outcome measure.

Rohit Aggarwal, MD, MS, is Medical Director of the Arthritis and Autoimmunity Center at the University of Pittsburgh School of Medicine.

Prof. Aggarwal’s research interests include myopathies such as polymyositis, dermatomyositis, and inclusion body myositis. His research and clinical areas of interest are clinical and translational research in inflammatory muscle diseases, and associated interstitial lung disease.

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