Programme | Speaker |
|---|---|
Welcome and Introduction | Andra Duncan, MD, MS, FASE |
Evidence–Practice Gap in the U.S.: Why Change Is Slow? | Kenichi Tanaka, MD |
National Implementation Case Study: Canada’s Transition to Factor-Based Care | Katerina Pavenski, MD, FRCPC |
Perspectives from Leading Experts: Aligning Evidence, Guidelines, and Practice | Markus Velten, MD |
Grace Lim, MD, MSc, MBA | |
Nadia Hensley, MD | |
Q&A and Closing Remarks |
United States17 October 2026
Bridging the Gap Between Clinical Evidence and Factor Concentrate Use
Octapharma Symposium at Anesthesiology 2026.
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Introduction
Growing clinical evidence is supporting the use of targeted factor concentrate therapy in perioperative bleeding management. Yet translating evidence into routine clinical practice remains challenging, with differences in institutional protocols, clinical pathways, multidisciplinary ownership and guideline adoption.
This symposium will explore how the gap between evidence and implementation can be addressed, with a particular focus on the US healthcare environment. Experts will review key clinical, safety and health-economic evidence and discuss the barriers that continue to influence the adoption of factor-based bleeding management strategies.
The faculty will also examine real-world experience with the transition towards factor-based care, exploring how evidence-based policy, standardised protocols, multidisciplinary collaboration and education can help translate clinical evidence into practice and support more consistent approaches to bleeding management.
Perspectives from leading medical societies will then explore how evolving evidence may inform guidelines, education and greater standardisation of care. The session will conclude with a multidisciplinary discussion on what successful implementation could look like in practice and the actions needed to move from evidence to protocols, guidelines and routine clinical practice.
Symposium programme
Saturday, 17 October, 12:00 - 13:00 hours PDT
Faculty
Chairperson: Andra Duncan, MD, MS, FASE
Andra Duncan, MD, MS, FASE
Professor, Division of Cardiothoracic Anesthesiology Vice Chair of Research, Department of Anesthesiology Cleveland Clinic, USA
Kenichi Tanaka, MD
Professor and Chair of the Department of Anesthesiology at OU College of Medicine, holding the John L. Plewes Professorship of Anesthesiology, USA.
Katerina Pavenski, MD, FRCPC
Head of the Division of Transfusion Medicine, clinical hematologist, medical director of the Therapeutic Apheresis and Patient Blood Management at St. Michael’s Hospital, Toronto, Canada.
Markus Velten, MD
Chief Cardiovascular and Thoracic Anesthesiology UT Southwestern Medical Center, Dallas, USA.
Grace Lim, MD, MSc, MBA
K.C. Wong Presidential Endowed Chair and Chair of the Department of Anesthesiology, Perioperative & Pain Medicine at the Spencer Fox Eccles School of Medicine, University of Utah Health. USA.
Nadia Hensley, MD
Associate Professor of Anesthesiology and Critical Care Medicine in the Adult Cardiothoracic Anesthesiology Division at the Johns Hopkins University School of Medicine. USA.
The symposium recording will be available on Science Hub following the congress.
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Sunday, October 18 | 10:15 PDT
Don't miss the E-Poster Presentation
Cost-effectiveness of Prothrombin Complex Concentrate vs. Frozen Plasma in Cardiac Surgery
Keyvan Karkouti, MD, FRCPC
University Health Network (UHN), and Sinai Health System, Toronto, Canada.
